609 research outputs found
Complete hyperfine Paschen-Back regime at relatively small magnetic fields realized in Potassium nano-cell
A one-dimensional nano-metric-thin cell (NC) filled with potassium metal has
been built and used to study optical atomic transitions in external magnetic
fields. These studies benefit from the remarkable features of the NC allowing
one to use - and -methods for effective investigations of
individual transitions of the K D_1 line. The methods are based on strong
narrowing of the absorption spectrum of the atomic column of thickness L equal
to and to (with \lambda = 770\un{nm} being the resonant
laser radiation wavelength). In particular, for a -polarized radiation
excitation the -method allows us to resolve eight atomic transitions
(in two groups of four atomic transitions) and to reveal two remarkable
transitions that we call Guiding Transitions (GT). The probabilities of all
other transitions inside the group (as well as the frequency slope versus
magnetic field) tend to the probability and to the slope of GT. Note that for
circular polarization there is one group of four transitions and GT do not
exist. Among eight transitions there are also two transitions (forbidden for
= 0) with the probabilities undergoing strong modification under the
influence of magnetic fields. Practically the complete hyperfine Paschen-Back
regime is observed at relatively low (\sim 1\un{kG}) magnetic fields. Note
that for K line GT are absent. Theoretical models describe the experiment
very well.Comment: 6 page
Giant modification of atomic transitions probabilities induced by magnetic field: forbidden transitions become predominant
Magnetic field-induced giant modification of probabilities for seven
components of 6S1/2 (Fg=3) - 6P3/2 (Fe=5) transition of Cs D2 line forbidden by
selection rules is observed experimentally for the first time. For the case of
excitation with circularly-polarized laser radiation, the probability of
Fg=3,mF=-3 - Fe=5,mF=-2 transition becomes the largest among 25 transitions of
Fg=3 - Fe=2,3,4,5 group in a wide range of magnetic field 200 - 3200 G.
Moreover, the modification is the largest among D2 lines of alkali metals. A
half-wave-thick cell (length along the beam propagation axis L=426 nm) filled
with Cs has been used in order to achieve sub-Doppler resolution which allows
for separating the large number of atomic transitions that appear in the
absorption spectrum when an external magnetic field is applied. For B > 3 kG
the group of seven transitions Fg=3 - Fe=5 is completely resolved and is
located at the high frequency wing of Fg=3 - Fe=2,3,4 transitions. The applied
theoretical model very well describes the experimental curves.Comment: 7 pages, 8 figure
Competition for hydrogen bond formation in the helix-coil transition and protein folding
The problem of the helix-coil transition of biopolymers in explicit solvents,
like water, with the ability for hydrogen bonding with solvent is addressed
analytically using a suitably modified version of the Generalized Model of
Polypeptide Chains. Besides the regular helix-coil transition, an additional
coil-helix or reentrant transition is also found at lower temperatures. The
reentrant transition arises due to competition between polymer-polymer and
polymer-water hydrogen bonds. The balance between the two types of hydrogen
bonding can be shifted to either direction through changes not only in
temperature, but also by pressure, mechanical force, osmotic stress or other
external influences. Both polypeptides and polynucleotides are considered
within a unified formalism. Our approach provides an explanation of the
experimental difficulty of observing the reentrant transition with pressure;
and underscores the advantage of pulling experiments for studies of DNA.
Results are discussed and compared with those reported in a number of recent
publications with which a significant level of agreement is obtained.Comment: 21 pages, 3 figures, submitted to Phys Rev
Analysis of the russian market of software products for real estate management
Active sanctions against Russia, including in the field of information technology, lead to a situation where the dependence of organizations on software products non-Russian origin may be a serious problem. Consequently, the task of analyzing the Russian software market, to which this article is devoted, seems relevant. The authors have reviewed one of the software classes – automation systems for real estate management, Computer Aided Facilities Management (hereinafter – CAFM-systems) in a foreign terminology. The article deals with the evaluation and ranking of software products, on the basis of which recommendations for their use in projects are formulated. For this purpose, a list has been formed consisting of twelve Russian CAFM-systems registered in the Unified Register of Russian Computer Programs and Databases; a set of evaluation parameters has been developed, divided into two groups – functional and non-functional parameters; an evaluation methodology using mathematical decision-making methods has been proposed; a group of experts has been formed; an expert evaluation and ranking of systems according to the developed methodology was conducted; a rating of systems with an indication of the companies-developers has been built. The results of the study show that the Russian market of CAFM-systems has been formed and provides customers interested in software products of this class with a fairly wide range of alternatives for choice. The conducted research, on the one hand, has practical value for specialists working with such software products, and, on the other hand, scientific value expressed in the proposed holistic methodology of market analysis, which can be extended to other types of software products by specifying a set of comparison parameters
Upgraded LED illuminator for colorimetric research
В статье описана экспериментальная осветительная установка с использованием стандартных светоизлучающих диодов. Управление яркостью светодиодных компонентов осуществляется при помощи автоматизированной системы, представляющей собой комплекс драйверов с широтно-импульсной модуляцией. Исследуемая экспериментальная осветительная установка предназначена для регулирования значения индекса цветопередачи при фиксированных цветности и общей яркости, что позволяет управлять визуально-воспринимаемой насыщенностью зелёных и красных цветов отражающих объектов.The article describes an experimental lighting system using standard light-emitting diodes. Brightness of light-emitting iodes components are managed using an automated system, which is a set of drivers with pulse width modulation. The researched experimental lighting system designed to regulate the value of the color rendering index at fixed chromaticity and brightness that makes possible to control visually perceived saturation of green and red colors reflecting objects
Оптимизация диагностической модели для прогнозирования эффективности химиолучевой терапии рака шейки матки на группе пациентов с коморбидными состояниями: когортное одноцентровое ретроспективное исследование
INTRODUCTION: Radiomics is a promising area of diagnostics. In clinical practice, ultrasound and magnetic resonance imaging are widely used for Cervical Cancer (CC). The lack of standards when carrying out examinations entails the problem of distinguishing different signs, i.e. there is no possibility to compare results of different institutions.OBJECTIVE: To review radiological diagnostic procedures and optimize a model to enable expanded large-scale multicentre mathematical analysis of radiological findings in comorbid women with CC.MATERIALS AND METHODS: The data from 362 magnetic resonance imaging (MRI) procedures (Philips Achieva, The Netherlands, 1.5T), 500 pelvic ultrasound procedures (US), and 500 retroperitoneal US in 77 comorbid women with cervical squamous cell cancer and cardiovascular disease, carried out between 2012 and 2022, were retrospectively examined. FIGO pretreatment stage 1А–4А. Age: 48.3±13.1. Follow-up period: 3.7±1.3 years.Statistics: Data analysis was carried out using the Stata 13 program (StataCorpLP, CollegeStation, TX, USA). The normality of the distribution of features was assessed using the Shapiro-Wilk criterion. The condition of equality of variances of the distribution of features was calculated according to the Leven criterion. For descriptive statistics of normally distributed features with equality of variances, the calculation of averages and standard deviations was used. Qualitative variables are represented as numbers (%). Logistic regression is performed. The significance level for all the methods used is set as p<0.05.RESULTS: The possibility of segmentation was 2.6% according to US and 100% according to MRI. We analyzed 1443 T2 TSE, 531 T1 TSE, 563 diffusion-weighted images (DWI), 389 STIR, 1987 post-contrast series (in 272 cases (75%) the study was accompanied by contrast agent administration). An MRI model for subsequent feature extraction in patients with CC should consist of T2TSE in the sagittal plane, DWI in the axial plane with automatic construction of apparent diffusion coefficient (ADC) maps.The most reproducible and valuable components of the model are found to be the DWI with automatic ADC map. The ADC value from the parametral fat significantly increased the probability of recurrence, and the cut-off point for ROC analysis was 1.1×10–3 mm2/sec.DISCUSSION: An analysis of medical ultrasound and MRI images in terms of their value for radiomics was carried out. According to the results, MRI is the preferred method. An important next step is to standardize series to extract additional value from diagnostic studies and to carry out multicentre retrospective studies using a multicomponent model.CONCLUSIONS: MRI is a reproducible and frequently used method with the ability to extract additional value from images. T2 TSE in the sagittal plane and DWI in the axial plane with automatic ADC map, followed by segmentation of the parametral area adjacent to the tumor, are considered the most frequently used techniques. Postcontrast imaging are not a reproducible technique and have no added value. A model MRI procedure to determine additional textural characteristics in patients with СС consists of T2-TSE in the sagittal plane, DWI in the axial plane with automatic ADC map.ВВЕДЕНИЕ: Перспективным направлением в диагностике является радиомика. В клинической практике при злокачественном новообразовании шейки матки (ЗНО ШМ) широко используется ультразвуковая и магнитно-резонансная диагностика. Отсутствие стандартов при проведении исследований влечет проблему выделения различных признаков, то есть отсутствие возможности сопоставления результатов работ разных учреждений.ЦЕЛЬ: Проанализировать процедуры лучевой диагностики и оптимизировать модель для возможности расширенного масштабного многоцентрового математического анализа результатов лучевых методов исследования у коморбидных пациенток со ЗНО ШМ.МАТЕРИАЛЫ И МЕТОДЫ: Ретроспективно изучены данные 362 процедур магнитно-резонансной томографии (МРТ) (Philips Achieva, Нидерланды, 1.5T), 500 процедур ультразвукового исследования (УЗИ) органов малого таза, 500 процедур УЗИ забрюшинного пространства у 77 коморбидных пациенток с плоскоклеточным ЗНО ШМ и сердечно-сосудистой патологией, выполненные в 2012–2022 гг. Стадия по FIGO до лечения — 1А–4А. Возраст — 48,3±13,1 года. Период наблюдения — 3,7±1,3 года.Статистика: Анализ данных проводился с использованием программы Stata 13 (StataCorpLP, CollegeStation, TX, USA). Нормальность распределения признаков оценивалась с помощью критерия Шапиро–Уилка. Условие равенства дисперсий распределения признаков рассчитывалось по критерию Левена. Для описательной статистики нормально распределенных признаков с равенством дисперсий использовалось вычисление средних значений и стандартных отклонений. Качественные переменные представлены в виде чисел (%). Выполнена логистическая регрессия. Уровень значимости для всех использующихся методов установлен как p<0,05.РЕЗУЛЬТАТЫ: По данным УЗИ возможность сегментации была в 2,6%, по данным МРТ — в 100%. Проанализировано 1443 T2 TSE, 531 T1 TSE, 563 диффузионно-взвешенных изображений (ДВИ), 389 STIR, 1987 постконтрастных серий (в 272 случаях (75%) исследование сопровождалось введением контрастного вещества). Модель МРТ для последующего извлечения признаков у больных ЗНО ШМ должна состоять из Т2-взвешенных изображений в сагиттальной плоскости, ДВИ в аксиальной плоскости с автоматическим построением карт измеряемого коэффициента диффузии (ИКД).Наиболее воспроизводимыми и ценными составляющими модели признаны ДВИ с автоматическим построением карт ИКД. Значение ИКД от зоны параметральной клетчатки значимо увеличивало вероятность рецидива, а при проведении ROC-анализа точка отсечения составила 1,1×10–3 мм2/с.ОБСУЖДЕНИЕ: Проведен анализ медицинских изображений УЗИ и МРТ в плане их ценности для радиомики. По результатам исследования МРТ является предпочтительным методом. Следующий важный шаг — стандартизация серий для извлечения дополнительной ценности из диагностических исследований и проведение многоцентровых ретроспективных исследований с использованием многокомпонентной модели.ЗАКЛЮЧЕНИЕ: Воспроизводимым и часто используемым методом с возможностью извлечения дополнительной ценности из изображений признана МРТ. Наиболее часто используемыми методиками признаны Т2 TSE в сагиттальной плоскости и ДВИ в аксиальной плоскости с автоматическим построением карт ИКД с последующей сегментацией зоны параметральной клетчатки, расположенной в непосредственной близости к опухоли. Постконтрастные изображения не являются воспроизводимой методикой и не имеют дополнительной ценности. Модель процедуры МРТ для определения дополнительных текстурных характеристик у пациенток с ЗНО ШМ состоит из Т2-взвешенных изображений в сагиттальной плоскости, ДВИ в аксиальной плоскости с автоматическим построением карт ИКД
Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC
The uncertainty on the calorimeter energy response to jets of particles is
derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the
calorimeter response to single isolated charged hadrons is measured and
compared to the Monte Carlo simulation using proton-proton collisions at
centre-of-mass energies of sqrt(s) = 900 GeV and 7 TeV collected during 2009
and 2010. Then, using the decay of K_s and Lambda particles, the calorimeter
response to specific types of particles (positively and negatively charged
pions, protons, and anti-protons) is measured and compared to the Monte Carlo
predictions. Finally, the jet energy scale uncertainty is determined by
propagating the response uncertainty for single charged and neutral particles
to jets. The response uncertainty is 2-5% for central isolated hadrons and 1-3%
for the final calorimeter jet energy scale.Comment: 24 pages plus author list (36 pages total), 23 figures, 1 table,
submitted to European Physical Journal
Standalone vertex finding in the ATLAS muon spectrometer
A dedicated reconstruction algorithm to find decay vertices in the ATLAS muon spectrometer is presented. The algorithm searches the region just upstream of or inside the muon spectrometer volume for multi-particle vertices that originate from the decay of particles with long decay paths. The performance of the algorithm is evaluated using both a sample of simulated Higgs boson events, in which the Higgs boson decays to long-lived neutral particles that in turn decay to bbar b final states, and pp collision data at √s = 7 TeV collected with the ATLAS detector at the LHC during 2011
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